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About Bipolar Disorder

Bipolar disorder is a mental illness characterized by the presence of at least one manic, mixed, or hypomanic episode. The presence of a Major Depressive Episode is very common in the lifetime of individuals with Bipolar Disorder (more than 90% of these individuals have at least one Major Depressive Episode in their lifetime), but it is not necessary to experience a depressive episode.

Some facts about bipolar disorder

  • An estimated 1-3% of the general population has bipolar disorder.
  • Bipolar disorder affects males and females at equal rates.
  • The peak age of onset of bipolar disorder is between the ages of 15 and 25.
  • Emil Kraeplin found that the average period of feeling "well" after a mood episode is:
    • 4.3 years after the 1st episode
    • 2.8 years after the 2nd episode
    • 1.8 years after the 3rd episode
    • 1.7 years after the 4th episode
    • 1.5 years after the 5th episode
  • We recommend considering 5 factors for a diagnosis of bipolar disorder:
    • Age of onset
    • Course of symptoms
    • Family history
    • Response to treatment
    • Current signs and symptom
The Massachusetts General Hospital
Bipolar Clinic and Research Program
50 Staniford Street, 5th Floor; Boston, MA 02114
P: (617) 726-5855 | F: (617) 726-6768

Treatment by clinic staff or MGH-affiliated clinics and studies can
NOT be arranged through this site or contact e-mail.


This web site, its contents, and contact information are designed for informational purposes only,
and must not be substituted for professional care.
Consult a physician or primary care doctor if you
believe that you are experiencing symptoms of any illness.
If you are experiencing an medical emergency, call 911 immediately.
© 2004 The MGH Bipolar Clinic and Research Program